1977-60-2

Basic information

• Product Name: ethyl 2-[4-(trifluoromethyl)phenyl]cyclopropanecarboxylate
• CAS NO: 1977-60-2
• Molecular Formula: C₁₃H₁₃F₃O₂
• Molecular Weight: 258.2363
• Mol File: 1977-60-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 283.775°C at 760 mmHg
• Flash Point: 98.158°C
• Density: 1.259g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.486
• CAS DataBase Reference: ethyl 2-[4-(trifluoromethyl)phenyl]cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-[4-(trifluoromethyl)phenyl]cyclopropanecarboxylate(1977-60-2)
• EPA Substance Registry System: ethyl 2-[4-(trifluoromethyl)phenyl]cyclopropanecarboxylate(1977-60-2)

Safety Data

• Hazardous Substances Data: 1977-60-2(Hazardous Substances Data)

Upstream product

• 2062-26-2 3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid 
• 1774-47-6 trimethylsulfoxonium iodide 
• 101466-85-7 ethyl (E)-4-trifluoromethylcinnamate 
• 623-73-4 diazoacetic acid ethyl ester 
• 402-50-6 1-trifluoromethyl-4-vinyl-benzene 

Relevant articles and documents

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Heterocyclic compounds of Formula (I) and pharmaceutically acceptable salt thereof are disclosed. The use of such heterocyclic compounds and pharmaceutically acceptable salt thereof for the treatment of cancers, and more particularly cancers sensitive to mitochondrial activity inhibition and increased reactive oxygen species (ROS) levels, is also disclosed. Such cancers include acute myeloid leukemia (AML), preferably AML characterized by certain features, such as high level of expression of one or more Homeobox (HOX)-network genes, high and/or low expression of specific genes, the presence of one or more cytogenetic or molecular risk factors such as intermediate cytogenetic risk, Normal Karyotype (A/K), mutated NPM1, mutated CEBPA, mutated FLT3, mutated DNMT3A, mutated TET2, mutated IDH1, mutated IDH2, mutated RUNX1, mutated WT1, mutated SRSF2, intermediate cytogenetic risk with abnormal karyotype (intern(abnK)), trisomy 8 (+8) and/or abnormal chromosome (5/7), and/or a high leukemic stem cell (LSC) frequency.

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Soluble Polymer-Supported Ruthenium Porphyrin Catalysts for Epoxidation, Cyclopropanation, and Aziridination of Alkenes

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