19770-52-6

Usage

InChI:InChI=1/C20H12/c1-3-7-16-13(5-1)11-15-12-14-6-2-4-8-17(14)19-10-9-18(16)20(15)19/h1-12H

Upstream product

• 108665-22-1 5,6-dihydroxy-1,2,3,4,5,6-hexahydrobenzaceanthrylene 
• 108665-21-0 5,6-dioxo-1,2,3,4,5,6-hexahydrobenzaceanthrylene 
• 108665-23-2 5-oxo-1,2,3,4,5,6-hexahydrobenzaceanthrylene 
• 108665-19-6 6-oxo-1,2,3,4,5,6-hexahydrobenzaceanthrylene 
• 5349-90-6 1,2,3,4-tetrahydronaphthacene-6,11-quinone 
• 1148-84-1 tetrahydro-1,2,3,4 naphtacene 
• 108665-20-9 1,2,3,4,5,6-hexahydrobenzaceanthrylene 

Relevant academic research and scientific papers

Synthesis of New Cyclopenta-Fused PAH Isomers of Cata-Annelated Benzenoid Systems

The syntheses of three new benz-annelated derivatives of aceanthrylene and acephenanthrylene are reported.These systems are of interest in studies on mechanisms of bioactivation and structure-activity correlations because of their predicted high level of biological activity.Of the three isomers, benzaceanthrylene (5) has been synthesized by two routes involving Friedel-Crafts acylations of 1,2,3,4-tetrahydronaphthacene with chloroacetyl chloride or oxalyl chloride as the key step.The cyclic ketone product from each route has been successfully elaborated to 5.Synthesis of benzaceanthrylene (9) involves preparation of acenaphthene-3,4-dicarboxylic anhydride and its smooth conversion to 9.A straightforward and high-yield synthesis of benzacephenanthrylene (27) is described utilizing a Robinson annelation reaction of methyl vinyl ketone with a previously reported ketonic precursor of acephenanthrylene.