197785-39-0

Basic information

• Product Name: 3-(4-Chloro-phenyl)-3-hydroxyamino-propionic acid
• Synonyms: 3-(4-Chloro-phenyl)-3-hydroxyamino-propionic acid
• CAS NO: 197785-39-0
• Molecular Weight: 215.636
• Mol File: 197785-39-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-Chloro-phenyl)-3-hydroxyamino-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Chloro-phenyl)-3-hydroxyamino-propionic acid(197785-39-0)
• EPA Substance Registry System: 3-(4-Chloro-phenyl)-3-hydroxyamino-propionic acid(197785-39-0)

Safety Data

• Hazardous Substances Data: 197785-39-0(Hazardous Substances Data)

Upstream product

• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 

Downstream Products

• 19947-39-8 3-amino-3-(4-chlorophenyl)propionic acid 

Relevant articles and documents

Potential GABAB receptor antagonists. IX: The synthesis of 3-amino-3-(4-chlorophenyl)propanoic acid, 2-amino-2-(4-chlorophenyl)ethylphosphonic acid and 2-amino-2-(4-chlorophenyl)ethanesulfonic acid

This paper describes the synthesis of 3-amino-3-(4-chlorophenyl)propanoic acid and the corresponding phosphonic and sulfonic acids, lower homologues of baclofen, phaclofen and saclofen respectively. The chlorinated acids were all weak specific antagonists of GABA at the GABAB receptor, with the sulfonic acid (pA2 4·0) being stronger than the phosphonic acid (pA2 3·8) and carboxylic acid (pA2 3·5).