1978-70-7

Basic information

• Product Name: PropanaMide, 2-Methyl-N-[4-(trifluoroMethyl)phenyl]-
• Synonyms: PropanaMide, 2-Methyl-N-[4-(trifluoroMethyl)phenyl]-;2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide
• CAS NO: 1978-70-7
• Molecular Formula: C₁₁H₁₂F₃NO
• Molecular Weight: 231.2142896
• Mol File: 1978-70-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PropanaMide, 2-Methyl-N-[4-(trifluoroMethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: PropanaMide, 2-Methyl-N-[4-(trifluoroMethyl)phenyl]-(1978-70-7)
• EPA Substance Registry System: PropanaMide, 2-Methyl-N-[4-(trifluoroMethyl)phenyl]-(1978-70-7)

Safety Data

• Hazardous Substances Data: 1978-70-7(Hazardous Substances Data)

Upstream product

• 78-82-0 Isobutyronitrile 
• 1232133-62-8 mesityl(4-(trifluoromethyl)phenyl)-λ³-iodanyl trifluoromethanesulfonate 

Relevant articles and documents

Ligand-free copper-catalyzed direct amidation of diaryliodonium salts using nitriles as amidation reagents

An efficient and practical methodology for the synthesis of N-arylamides has been developed via copper-catalyzed amidation of diaryliodonium salts with nitriles. Various substituted aryl nitriles and aliphatic nitriles could be applied in the reaction, providing a series of N-arylated amides in moderate to good yields. This procedure provides an alternative route for the synthesis of various N-arylamides. A proposed mechanism based on control experiments is also presented.