19781-26-1

Basic information

• Product Name: 4-ETHYL-3-OCTANOL
• Synonyms: 4-ETHYL-3-OCTANOL;4-Ethyl-3-octanol, threo + erythro, 99%;4-Ethyl-3-octanol, erythro + threo, 99%;4-Ethyl-3-octanol(mixtureofthreoanderythro)
• CAS NO: 19781-26-1
• Molecular Formula: C₁₀H₂₂O
• Molecular Weight: 158.28
• Mol File: 19781-26-1.mol

Chemical Properties

• Boiling Point: 206.4°Cat760mmHg
• Flash Point: 87.9°C
• Appearance: /
• Density: 0.824g/cm³
• Vapor Pressure: 0.0561mmHg at 25°C
• Refractive Index: 1.432
• CAS DataBase Reference: 4-ETHYL-3-OCTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYL-3-OCTANOL(19781-26-1)
• EPA Substance Registry System: 4-ETHYL-3-OCTANOL(19781-26-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 19781-26-1(Hazardous Substances Data)

Usage

Uses

Used in Fragrance Industry:
4-Ethyl-3-octanol is used as a fragrance ingredient for its floral scent, adding pleasant aromas to personal care and household products.
Used in Food Industry:
4-Ethyl-3-octanol is used as a flavoring agent for enhancing the taste and aroma of beverages and confectionery products.
Used in Chemical and Pharmaceutical Manufacturing:
4-Ethyl-3-octanol is used as a building block in the synthesis of other chemicals and pharmaceuticals, contributing to the development of various products.

InChI:InChI=1/C10H22O/c1-4-7-8-9(5-2)10(11)6-3/h9-11H,4-8H2,1-3H3/t9-,10-/m1/s1

Upstream product

• 123-05-7 d,l-2-ethylhexanal 
• 925-90-6 ethylmagnesium bromide 
• 5877-42-9 4-ethyl-1-octyn-3-ol 

Relevant articles and documents

METHOD FOR PRODUCING A PROPARGYL ALCOHOL AND AN ALLYL ALCOHOL

The invention relates to a method for producing a propargyl alcohol of formula (I) wherein R1 represents a C1-30 alkyl radical, a C3-8 cycloalkyl radical, a C2-20 alkoxyalkyl radical, a C6-14 aryl radical, a C7-20 alkoxyaryl radical, a C7-20 aralkyl radical, a C7-20 alkylaryl radical or H. According to said method, a corresponding aldehyde of formula R1-CHO is reacted with acetylene in the presence of ammonia and a catalytic quantity of between 0.6 and 10 mol % of an alkaline metal hydroxide, an alkaline earth metal hydroxide or an alkaline metal alcoholate, in relation to the aldehyde used. The invention also relates to a method for producing an allyl alcohol of formulae (II) and (III), from the propargyl alcohol (I) produced according to the invention.

Highly regioselective reaction of zirconocene-alkene complexes with aldehydes or ketones

Reactions of zirconocene-alkene complexes Cp2Zr(CH2=CHR)(PR'3) (R = H, Me, Et, SiR"3 or Ar) with aldehydes or ketones were investigated.Zirconocene-ethylene, -propylene or 1-butene complexes reacted with aldehydes or ketones at terminal carbons of alkenes to give the corresponding alcohols after hydrolysis with a high regioselectivity.A similar type of reaction product was also obtained by a reaction of zirconacyclopentanes with aldehydes.This reaction proceeded via β-β' carbon-carbon bond cleavage of zirconacyclopentanes.A reaction of zirconocene-vinylsilane complexes with ketones afforded 3-trimethylsilyl-1-oxa-2-zirconacyclopentanes with an excellent regioselectivity.Carbon-carbon bond formation occurred exclusively at the terminal carbon of vinylsilanes.Their corresponding γ-silylalcohols were obtained after hydrolysis.The products showed that vinylsilanes reacted with carbonyl compounds at the β-carbon to silyl group.It is in sharp contrast to the conventional reactions of vinylsilanes of which the α-carbon normally attacked electrophiles.The reactions of styrene and its derivatives with pentan-3-one on zirconium gave a mixture of two regioisomers.Substituents of alkenes tend to be in α-position to Zr in 1-oxa-2-zirconacyclopentanes.This orientation showed a different aspect of the formation of 1-oxa-2-zirconacyclopentanes from the alkene-alkene coupling reaction on zirconium.The regioselectivity of the reaction with carbonyl compounds decreased in this order; R = alkyl > silyl > aryl. Key words: Zirconium; Silicon; Metallocenes; Carbon-carbon bond formation; Aldehyde; Ketone

Zirconium Mediated Regioselective Carbon-Carbon Bond Formation Reactions

Reactions of zirconocene-alkene complexes with aldehydes gave alcohols as coupling products after hydrolysis.The carbon-carbon bond formation proceeded at C1 carbon of alkenes, in sharp contrast to the reactions of alkene-alkene coupling on zirconium.A similar alcohol was also obtained by the reaction of zirconacyclopentane with aldehyde after hydrolysis.Treatment of (C5Me5)2ZrEt2 with styrene gave 2-phenylbutane after hydrolysis contrary to the case of Cp2ZrEt2 which afforded 1-phenylbutane.