197895-16-2Relevant articles and documents
Synthesis, structure-activity relationships, and pharmacological profile of 9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-hi]indoles: Discovery of potent, selective phosphodiesterase type 4 inhibitors
Burnouf,Auclair,Avenel,Bertin,Bigot,Calvet,Chan,Durand,Fasquelle,Féru,Gilbertsen,Jacobelli,Kebsi,Lallier,Maignel,Martin,Milano,Ouagued,Pascal,Pruniaux,Puaud,Rocher,Terrasse,Wrigglesworth,Doherty
, p. 4850 - 4867 (2000)
The synthesis, structure-activity relationships, and biological properties of a novel series of potent and selective phosphodiesterase type 4 (PDE4) inhibitors are described. These new aminodiazepinoindoles displayed in vitro PDE4 activity with submicromo
