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1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE is a cationic antibiotic with broad-spectrum antibacterial activity. It is a member of the cephamycin class of antibiotics, derived from cephamycin C, and is particularly effective against bacteria that are resistant to penicillin and other antibiotics. 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE works by inhibiting bacterial cell wall synthesis, leading to the disruption of the bacterial cell structure and ultimately causing bacterial death. It serves as an important therapeutic agent for the treatment of various bacterial infections in clinical settings.

197897-11-3

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Basic information
1. Product Name: 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE
2. Synonyms: 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE;1-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]imidazo[1,2-b]pyridazinium iodide;1-[((7R)-7-aMino-4-carboxy-3,4-didehydrochephaM-3-yl)Methyl]-1H-iMidazo[1,2-b] pyridazin-4-iuM Iodide;(6R,7R)-7-AMino-3-(iMidazo[1,2-b]pyridazin-1(5H)-ylMethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydroiodide;(6R,7R)-7-Amino-3-(imidazo[1,2-b]pyridazin-1(5H)-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-;(6R,7R)-7-Amino-3-(imidazo[1,2-b]pyridazin-1(5H)-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct
3. CAS NO:197897-11-3
4. Molecular Formula: C14H16IN5O3S
5. Molecular Weight: 461.27801
6. EINECS: 1312995-182-4
7. Product Categories: N/A
8. Mol File: 197897-11-3.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE(CAS DataBase Reference)
10. NIST Chemistry Reference: 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE(197897-11-3)
11. EPA Substance Registry System: 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE(197897-11-3)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 197897-11-3(Hazardous Substances Data)

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197897-11-3 Usage

Uses

Used in Clinical Medicine:
1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE is used as an antibiotic for the treatment of bacterial infections that are resistant to common antibiotics such as penicillin. Its broad-spectrum activity and ability to inhibit bacterial cell wall synthesis make it a valuable tool in combating antibiotic-resistant bacteria.
Used in Research and Development:
In the field of microbiology and pharmaceutical research, 1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE is used as a research compound to study the mechanisms of bacterial resistance and to develop new strategies for combating antibiotic resistance.
Used in Pharmaceutical Industry:
1-[((7R)-7-AMINO-4-CARBOXY-3,4-DIDEHYDROCEPHAM-3-YL)METHYL]-1H-IMIDAZO[1,2-B]PYRIDAZIN-4-IUM IODIDE is utilized in the development of new antibiotics and formulations to address the growing challenge of antibiotic resistance in various bacterial infections. Its unique mechanism of action and effectiveness against resistant strains make it a promising candidate for the creation of novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 197897-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,8,9 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 197897-11:
(8*1)+(7*9)+(6*7)+(5*8)+(4*9)+(3*7)+(2*1)+(1*1)=213
213 % 10 = 3
So 197897-11-3 is a valid CAS Registry Number.

197897-11-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,hydroiodide

1.2 Other means of identification

Product number	-
Other names	7-amino-3-[(imidazo[1,2-b]pyridazinium-1-yl)methyl]-3-cephem-4-carboxylate hydroiodide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:197897-11-3 SDS

197897-11-3Synthetic route

: 89604-91-1
(Z)-(5-amino-[1,2,4]thiadiazol-3-yl)methoxyiminothioacetic acid S-benzothiazol-2-yl ester

: 197897-11-3
7-amino-3-[(imidazo[1,2-b]pyridazinium-1-yl)methyl]-3-cephem-4-carboxylate hydroiodide

: cefozopran

Conditions

Conditions	Yield
With tributyl-amine In tetrahydrofuran; water at 20 - 25℃; for 15h; Large scale reaction;	95%

197897-11-3Upstream product

197897-11-3Downstream Products

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