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1979-97-1

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1979-97-1 Usage

General Description

2-(Methylthio)-5-nitropyrimidine-4,6-diol is a chemical compound with the molecular formula C5H6N4O3S. It is a nitrosoamine derivative that contains a sulfur atom and a nitro group, making it a potentially hazardous and reactive compound. Its primary use is as an intermediate in the synthesis of pharmaceuticals and agrochemicals. In addition, it has been studied for its potential anti-inflammatory and anti-cancer properties. Due to its potential reactivity and hazardous nature, proper handling and storage protocols should be followed when working with this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 1979-97-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 9 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1979-97:
(6*1)+(5*9)+(4*7)+(3*9)+(2*9)+(1*7)=131
131 % 10 = 1
So 1979-97-1 is a valid CAS Registry Number.

1979-97-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-2-methylsulfanyl-5-nitro-1H-pyrimidin-6-one

1.2 Other means of identification

Product number -
Other names 2-methylsulfanyl-5-nitro-1H-pyrimidine-4,6-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1979-97-1 SDS

1979-97-1Relevant articles and documents

NEW PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF GRAM-NEGATIVE BACTERIAL INFECTION, CONTAMINATION AND FOULING

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Page/Page column 86, (2020/10/28)

New pyrimidine derivatives together with a membrane penetrating agent, optionally with a detectable isotope and pharmaceutical composition for use in treatment or prevention of Gram-negative bacterial infection in a host mammal in need of such treatment or prevention and use as inhibitors of Gram-negative biofilm formation on a surface of biomaterial or medical device, particularly of cardiovascular device such as prosthetic heart valve or pacemakers. New pyrimidine derivatives together with a membrane penetrating agent; for use as radiotracer in diagnosing or prognosing Gram-negative bacterial infection in a host mammal.

Soluble guanylate cyclase stimulators for the treatment of hypertension: Discovery of MK-2947

Brockunier, Linda,Stelmach, John,Guo, Jian,Spencer, Tracy,Rosauer, Keith,Bansal, Alka,Cai, Sheng-Jian,Chen, Nancy,Cummings, John,Huang, Li,Johnson, Timothy,Levesque, Sonia,Luo, Lin,Maloney, Kevin,Metzger, Joseph,Mortko, Christopher,Ortega, Karen,Pai, Lee-Yuh,Pereira, Antonio,Salituro, Gino,Shang, Jackie,Shepherd, Cherrie,Sherrie Xu, Shiyao,Yang, Qifeng,Cui, Jisong,Roy, Sophie,Parmee, Emma,Raghavan, Subharekha

supporting information, (2020/10/12)

The NO-sGC-cGMP signaling pathway plays an important role in the cardiovascular system. Loss of nitric oxide tone or impaired signaling has been associated with cardiovascular diseases, such as hypertension, pulmonary hypertension and heart failure. Direct activation of sGC enzyme independent of NO represents a novel approach for modulating NO signaling with tremendous therapeutic potential. Herein, we describe the design of a structurally novel class of heme-dependent sGC stimulators containing the 3,3-dimethylpyrrolidin-2-one moiety which resulted in the identification of the potent, selective stimulator 30 (MK-2947) for the treatment of hypertension.

PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS

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Page/Page column 74; 75, (2019/09/04)

New pyrimidine derivatives of formula (I), optionally with a detectable isotope, pharmaceutical composition and method of preparation thereof. New pyrimidine derivatives for use in treatment or prevention of bacterial infection in a host mammal in need of such treatment or prevention and use as inhibitors of biofilm formation on a surface of biomaterial or medical device, particularly of cardiovascular device such as prosthetic heart valve or pacemakers. New pyrimidine derivatives for use as radiotracer in diagnosing or prognosing bacterial infection in a host mammal.

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