197904-11-3

Basic information

• Product Name: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-cis)- (9CI)
• Synonyms: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-cis)- (9CI);Ethyl (1S,2R)-2-AMinocyclopentanecarboxylate
• CAS NO: 197904-11-3
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.2102
• Product Categories: CARBOXYLICESTER
• Mol File: 197904-11-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-cis)- (9CI)(197904-11-3)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-cis)- (9CI)(197904-11-3)

Safety Data

• Hazardous Substances Data: 197904-11-3(Hazardous Substances Data)

Usage

Uses

Ethyl (1S,2R)-2-aminocyclopentanecarboxylate is a heterocyclic compound mainly used in organic synthesis.?

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 1140972-24-2 C₈H₈O₃*C₁₅H₂₀FNO₂ 
• 1609100-30-2 ethyl cis-2-aminocyclopentane-1-carboxylate 

Downstream Products

• 1140972-31-1 (1S,2R)-2-tert-butoxycarbonylaminocyclopentanecarboxylic acid ethyl ester 

Relevant articles and documents

Expanding dynamic kinetic protocols: Transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives

Several α-alkylated β-amino esters have been obtained via DKR processes employing a kit of transaminases and isopropylamine as an amino donor in aqueous medium under mild conditions. Thus, while acyclic α-alkyl-β-keto esters afforded excellent conversions and enantioselectivities, although usually low diastereoselectivities, using more constrained cyclic β-keto esters high to excellent inductions were obtained.

The first direct enzymatic hydrolysis of alicyclic β-amino esters: A route to enantiopure cis and trans β-amino acids

The first direct enzymatic method is reported for the synthesis of cis and trans βamino acid enantiomers through the lipase-catalyzed enantioselective hydrolysis of alicyclic β esters in organic media. High enantioselectivities (E usually > 001) were observed when the Candida antarctica lipase B catalyzed reactions were performed with H2O (0.5 equivalents) in iP iPr2O at 5°C. The resolved products, obtained in good yields (≥42%), could be easily separated.