197960-05-7Relevant articles and documents
AMIDINOHYDRAZONES AS PROTEASE INHIBITORS
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Page/Page column 35, (2010/11/23)
Amidino and benzamidino compounds, including compounds of the formula: I wherein R1-R4, R6-R9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of Formula I.