197969-46-3Relevant academic research and scientific papers
Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand
Plummer, Mark S.,Holland, Debra R.,Shahripour, Aurash,Lunney, Elizabeth A.,Fergus, James H.,Marks, James S.,McConnell, Patrick,Thomas Mueller,Sawyer, Tomi K.
, p. 3719 - 3725 (2007/10/03)
The specific association of an SH2 domain with a phosphotyrosine (pTyr)- containing sequence of another protein precipitates a cascade of intracellular molecular interactions (signals) which effect a wide range of intracellular processes. The nonreceptor
