198012-22-5

Upstream product

• 198012-19-0 Thioacetic acid S-[(2R,3R,4S,5R)-2-acetylamino-3,4,6-tris-benzyloxy-5-hydroxy-1-(2-trimethylsilanyl-ethoxy)-hexyl] ester 
• 198012-20-3 Thioacetic acid S-[(2R,3R,4R)-2-acetylamino-3,4,6-tris-benzyloxy-5-oxo-1-(2-trimethylsilanyl-ethoxy)-hexyl] ester 
• 198012-18-9 N-[(2R,3R,4R,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-(2-trimethylsilanyl-ethoxy)-tetrahydro-pyran-3-yl]-acetamide 
• 198012-21-4 Thioacetic acid S-[(2R,3R,4S,5S)-2-acetylamino-3,4,6-tris-benzyloxy-5-hydroxy-1-(2-trimethylsilanyl-ethoxy)-hexyl] ester 

Downstream Products

• 198012-25-8 Acetic acid (2R,3R,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-(bis-benzyloxy-phosphoryloxy)-tetrahydro-thiopyran-4-yl ester 

Relevant academic research and scientific papers

UDP-N-acetyl-5-thio-galactosamine is a substrate of lactose synthase

Uridine 5'-(N-acetyl-5-thio-galactosaminyl diphosphate) (UDP-5SGalNAc) was synthesized from an N-acetylgalactosamine derivative via ring opening-recyclization approach. UDP-5SGalNAc was active as a donor substrate for lactose synthase, the complex of galactosyltransferase and lactalbumin, giving the disaccharide mimic (5SGalNAcβ[1→4]GlcNAc) which has a sulfur in the ring of the non-reducing sugar. The initial rate of the formation of the disaccharide mimic was 0.23% that for the natural disaccharide (GalNAcβ[1→4]GlcNAc).