198014-18-5Relevant academic research and scientific papers
A radical based addition-elimination route for the preparation of indoles
Murphy, John A.,Scott, Karen A.,Sinclair, Rhoha S.,Martin, Concepcion Gonzalez,Kennedy, Alan R.,Lewis, Norman
, p. 2395 - 2408 (2000)
Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using "clean methodology" either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides. The Royal Society of Chemistry 2000.
A new synthesis of indoles
Murphy, John A.,Scott, Karen A.,Sinclair, Rhona S.,Lewis, Norman
, p. 7295 - 7298 (2007/10/03)
Aryl radical cyclisation onto appropriate vinyl bromides leads to a new route to indoles.
