198014-57-2Relevant academic research and scientific papers
Asymmetric synthesis of all four isomers of topographically constrained novel amino acids: β-isopropyltyrosines
Lin, Jun,Liao, Subo,Han, Yinglin,Qiu, Wei,Hruby, Victor J.
, p. 3213 - 3221 (2007/10/03)
All four stereoisomers of the highly constrained novel amino acid, β-isopropyltyrosine, have been synthesized with high stereoselectivities (>90% de) and in 40-50% overall yields by using the optically pure 4-phenyloxazolidinone as a chiral auxiliary via asymmetric Michael addition, direct or indirect azidation, hydrogenolysis and demethylation reactions.
