198021-38-4

Basic information

• Product Name: 2-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)acetic acid
• Synonyms: 2-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)acetic acid
• CAS NO: 198021-38-4
• Molecular Formula: C₁₇H₁₅NO₄
• Molecular Weight: 297
• Mol File: 198021-38-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)acetic acid(198021-38-4)
• EPA Substance Registry System: 2-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)acetic acid(198021-38-4)

Safety Data

• Hazardous Substances Data: 198021-38-4(Hazardous Substances Data)

Usage

Usage

Antibacterial agent

Specific application

Treatment of skin and soft tissue infections caused by Gram-positive bacteria

Mechanism of action

Inhibits protein synthesis in bacteria, preventing growth and reproduction

Administration route

Oral, well-absorbed

Potential issues

Side effects, interactions with other medications, and development of antibiotic resistance

Importance

Valuable alternative for treating bacterial infections

Upstream product

• 1147849-07-7 ethyl [(4S,5R)-4,5-diphenyloxazolidin-2-on-3-yl]acetate 

Downstream Products

• 1217258-84-8 tert-butyl-2-((3S,4R)-2-oxo-3-((4S,5R)-2-oxo-4,5-diphenyloxazolidin-3-yl)-4-((E)-styryl)azetidin-1-yl)acetate 
• 198022-12-7 (4S,5R)-3-[(3S,4R)-1-(Bis-trimethylsilanyl-methyl)-2-oxo-4-phenethyl-azetidin-3-yl]-4,5-diphenyl-oxazolidin-2-one 
• 198022-11-6 (4S,5R)-3-[(3S,4R)-1-(Bis-trimethylsilanyl-methyl)-2-oxo-4-propyl-azetidin-3-yl]-4,5-diphenyl-oxazolidin-2-one 
• 198021-47-5 (4S,5R)-3-[(2S,3S)-1-(Bis-trimethylsilanyl-methyl)-2-methyl-4-oxo-azetidin-3-yl]-4,5-diphenyl-oxazolidin-2-one 
• 198021-44-2 (3S,4R)-1-[bis(trimethylsilyl)methyl]-4-methyl-3-[(4S,5R)-4,5-diphenyl-2-oxo-oxazolidin-3-yl]-azetidin-2-one 
• 198022-19-4 (4S,5R)-3-[(2S,3S)-2-Benzyloxymethyl-1-(bis-trimethylsilanyl-methyl)-4-oxo-azetidin-3-yl]-4,5-diphenyl-oxazolidin-2-one 
• 198022-17-2 (3S,4R)-1-[bis(trimethylsilyl)methyl]-4-phenyl-3-[(4S,5R)-4,5-diphenyl-2-oxo-oxazolidin-3-yl]-azetidin-2-one 

Relevant articles and documents

A practical synthesis of enantiopure 4,4,4-trifluoro-allo-threonine from an easily available fluorinated building block

A practical method to prepare enantiopure 4,4,4-trifluoro-allo-threonine was developed by using an easily available fluorinated building block and a chiral auxiliary as starting materials. Trifluoroacetic anhydride was annulated with a ketene, derived fro

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem -lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar1, Ar2, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem β-lactam antibiotics having the following chemical structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, R1, R2 and R3 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.