19812-99-8Relevant academic research and scientific papers
Studies of the asymmetric [2+2] cycloaddition of silylketenes and aldehydes employing Ti-TADDOL catalysts
Yang, Hong Woon,Romo, Daniel
, p. 2877 - 2880 (1998)
Ti-TADDOL catalysts provide good reactivity and moderate enantioselectivity in the asymmetric [2+2] cycloaddition of silyl ketenes and aldehydes. The effects of potential bidentate chelation of benzyloxy substituted aldehydes and of the steric size of the ketene silyl group were studied.
A novel synthesis of β-sulfinyl- and β-sulfonyl-hydroxamic acids via CsF-mediated ring opening of substituted β-lactones
Rossé,Gerber,Specklin,Hubschwerlen
, p. 538 - 540 (2007/10/03)
The ring-opening reaction of 3-substituted β-lactones with thiols was achieved using CsF in DMF as promoter. The resulting β-sulfanyl-carboxylic acid intermediates were coupled to hydroxylamine-Wang resin and the sulfur atom was selectively oxidized to afford β-sulfinyl- and β-sulfonyl-hydroxamic acid libraries.
