198205-79-7

Basic information

• Product Name: 2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID
• Synonyms: 2'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-4-CARBOXYLIC ACID;2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID;AKOS BAR-0022;Trifluoromethylbiphenyl-4-carboxylic acid;4-(2-(Trifluoromethyl)phenyl)benzoic acid;4-(2,4-Bis(trifluoromethyl)phenyl)benzoic acid;2'-Trifluoromethyl-biphenyl-4-carboxylic acid
• CAS NO: 198205-79-7
• Molecular Formula: C₁₄H₉F₃O₂
• Molecular Weight: 266.22
• Product Categories: Biphenyl & Diphenyl ether
• Mol File: 198205-79-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 380.8 °C at 760 mmHg
• Flash Point: 184.1 °C
• Appearance: /
• Density: 1.326 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID(198205-79-7)
• EPA Substance Registry System: 2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID(198205-79-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 198205-79-7(Hazardous Substances Data)

Usage

General Description

2'-Trifluoromethylbiphenyl-4-carboxylic acid is a chemical compound with the molecular formula C14H9F3O2. It is a derivative of biphenyl, containing a carboxylic acid group at the 4-position and a trifluoromethyl group at the 2'-position. 2'-TRIFLUOROMETHYLBIPHENYL-4-CARBOXYLIC ACID is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of various organic compounds. 2'-Trifluoromethylbiphenyl-4-carboxylic acid has potential applications in the fields of medicinal chemistry and materials science due to its unique chemical structure and properties.

Upstream product

• 198205-95-7 2'-(trifluoromethyl)biphenyl-4-carbaldehyde 
• 513-35-9 2-methyl-but-2-ene 

Downstream Products

• 726135-20-2 N-(2-hydroxy-2-phenylethyl)-N-methyl-2'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide 
• 1355682-04-0 C₂₀H₁₅F₃N₂O₄S 
• 1141474-63-6 methyl 2-fluoro-4-{5-[2'-(trifluoromethyl)biphenyl-4-yl]-1,2,4-oxadiazol-3-yl}benzoate 

Relevant articles and documents

BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

Disclosed is a novel biaryl amide derivative represented by formula (1) and having an affinity for the aldosterone receptor; also disclosed is a pharmaceutically acceptable salt thereof. (In the formula, A is any of the groups represented by formula (a); L is —CONH—, etc.; R1 is a substitutable aminosulfonyl group, etc.; R2 is a hydrogen atom, etc.; R3 is a hydrogen atom, etc.; R4 is a hydrogen atom, a halogen atom, hydroxy group, a substitutable amino group, a substitutable C1-6 alkoxy group, a substitutable 4- to 7-membered cyclic amino group, etc.; R5a, R5b and R5c are each independently hydrogen atoms, etc.; R6 is a halogen atom, a cyano group, etc.; R7 and R8 are each independently a hydrogen atom, etc.; and m is an integer such as 0.)

HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES

The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof, which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases

HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES

The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof, which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases