198219-19-1

Basic information

• Product Name: 1,3-Dimethyl-5-(4-phenoxy-but-2-ynyloxy)-1H-pyrimidine-2,4-dione
• Synonyms: 1,3-Dimethyl-5-(4-phenoxy-but-2-ynyloxy)-1H-pyrimidine-2,4-dione
• CAS NO: 198219-19-1
• Molecular Weight: 300.314
• Mol File: 198219-19-1.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dimethyl-5-(4-phenoxy-but-2-ynyloxy)-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dimethyl-5-(4-phenoxy-but-2-ynyloxy)-1H-pyrimidine-2,4-dione(198219-19-1)
• EPA Substance Registry System: 1,3-Dimethyl-5-(4-phenoxy-but-2-ynyloxy)-1H-pyrimidine-2,4-dione(198219-19-1)

Safety Data

• Hazardous Substances Data: 198219-19-1(Hazardous Substances Data)

Upstream product

• 20406-86-4 1,3-dimethyl-5-hydroxyuracil 
• 90797-91-4 1-chloro-4-phenoxybut-2-yne 

Downstream Products

• 1044220-84-9 C₁₆H₁₆N₂O₄ 
• 198219-25-9 1,3-Dimethyl-8-phenoxymethyl-1H,6H-pyrano[3,2-d]pyrimidine-2,4-dione 

Relevant articles and documents

Regioselective synthesis of pyrano[3,2-c]pyrimidine derivatives via a palladium-catalyzed unusual [1,3] aryloxy shift and cycloisomerization: first report of a [1,3] shift of an aryloxy group

Uracil-annulated pyrano heterocycles are regioselectively synthesized in excellent yields (92-100%) via a palladium-catalyzed unusual [1,3] aryloxy shift followed by 6-endo dig cyclization and [1,3] prototropic shift.

Regioselective synthesis of 6H-pyrano[3,2-e]pyrimidine-2,4-dione

7-Aryloxymethyl-1,3-dimethyl-6H-pyrano[3,2-e]pyrimidine-2,4-diones (4a- f) were synthesized in 88-92% yields (isolated) by the regioselectively thermal [3s, 3s] sigmatropic rearrangement of 1,3-dimethyl-5-(1-aryloxybut- 2-ynyloxy)pyrimidine-2,4-diones, (3