198277-10-0

Basic information

• Product Name: 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester
• Synonyms: 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester
• CAS NO: 198277-10-0
• Molecular Weight: 375.216
• Mol File: 198277-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester(198277-10-0)
• EPA Substance Registry System: 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester(198277-10-0)

Safety Data

• Hazardous Substances Data: 198277-10-0(Hazardous Substances Data)

Upstream product

• 198277-06-4 2-(5-bromo-2-hydroxyphenyl)-1-ethanol 
• 685-87-0 Diethyl 2-bromomalonate 

Relevant articles and documents

HETEROCYCLIC BETA-ADRENERGIC AGONISTS

The present invention relates to certain compounds of the formula (I) the racemic-enantiomeric mixtures and optical isomers of said compounds and the pharmaceutically acceptable salts or prodrugs thereof, depicted below, which are β-adrenergic receptor agonists and accordingly have utility as, inter alia, hypoglycemic and antiobesity agents. More specifically, the compounds of the instant invention are selective agonists of β 3-adrenergic receptor. The invention also relates to methods of use for the compounds and to pharmaceutical compositions containing them. The compounds of the present invention also possess utility for increasing lean meat deposition and/or improving the lean meat to fat ratio in animals, e.g., ungulate animals, companion animals and poultry. The compounds have the formula STR1 wherein R. sup.1, R. sup.2, R 3, R 4, R 5, Y and Z are as defined in the specification.