1984-06-1

Basic information

• Product Name: Sodium octanoate
• Synonyms: Octanoic acid, sodiuMsalt (1:1);Sodium n-caprylate;Sodium caprylate, Octanoic acid sodium salt;Caprylic acid sodium salt≥ 99% (anhydrous assay);Caprylic acid sodium salt Octanoic acid sodium salt Sodium caprylate n-Octanoic Acid Sodium Salt Sodium n-Octanoate;CAPRYLIC ACID SODIUM SALT;OCTANOIC ACID SODIUM SALT;N-OCTANOIC ACID SODIUM SALT
• CAS NO: 1984-06-1
• Molecular Formula: C₈H₁₅O₂*Na
• Molecular Weight: 166.19
• EINECS: 217-850-5
• Product Categories: API intermediates
• Mol File: 1984-06-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: ~245 °C (dec.)
• Boiling Point: 239.3 °C at 760 mmHg
• Flash Point: 107.4 °C
• Appearance: White to off-white/Powder
• Density: 1.188 at 20℃
• Vapor Pressure: 0.022mmHg at 25°C
• Storage Temp.: Store at RT.
• Solubility: H2O: 50 mg/mL, clear
• Water Solubility: soluble
• Stability: Stable. Incompatible with strong oxidizing agents.
• BRN: 3597723
• CAS DataBase Reference: Sodium octanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium octanoate(1984-06-1)
• EPA Substance Registry System: Sodium octanoate(1984-06-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• RTECS: RH0787000
• TSCA: Yes
• Hazardous Substances Data: 1984-06-1(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Different sources of media describe the Uses of 1984-06-1 differently. You can refer to the following data:
1. Excipient.
2. Sodium octanoate is the sodium salt of caprylic acid. It functions as a binder, emulsifier, and anticaking agent.
3. Sodium octanoate may be used as a protein stabilizer for molecules such as albumin and fibrinogen under conditions such heat sterilization. Also used for blood plasma fractionation.

Definition

ChEBI: An organic sodium salt comprising equal numbers of sodium and octanoate ions.

Clinical Use

Sodium caprylate is prepared from caprylic acid, which is acomponent of coconut and palm oils. The salt precipitates ascream-colored granules that are soluble in water and sparinglysoluble in alcohol.Sodium caprylate is used topically to treat superficialdermatomycoses caused by C. albicans and Trichophyton,Microsporum, and Epidermophyton spp. The sodium saltcan be purchased in solution, powder, and ointment forms.

InChI:InChI=1/C8H16O2.Na/c1-2-3-4-5-6-7-8(9)10;/h2-7H2,1H3,(H,9,10);

Upstream product

• 124-07-2 Octanoic acid 
• 117707-38-7 (R)-2-octyl octanoate 
• 1956-10-1 p-nitrophenyl-caprylate 
• 594-01-4 1-chloroethanol 
• 93163-88-3 phenacyl octanoate 
• 141-53-7 sodium formate 
• 111-87-5 octanol 

Downstream Products

• 110-43-0 n-pentyl methyl ketone 
• 3890-89-9 copper(II) octanoate 
• 111-64-8 n-octanoic acid chloride 
• 10264-16-1 N-butyl-butyramide 
• 24928-30-1 N-butyloctanamide 
• 35300-58-4 octanoic acid para-nitrobenzyl ester 
• 24927-67-1 silver octanoate 
• 79321-04-3 neodymium(III) heptanoate 
• 557-09-5 zinc(II) octanoate 
• 127421-29-8 {Pd(H21C10OC6H3CH=NN=CHC6H4OC10H21)(μ-O2CC7H15)}2 
• 10603-63-1 Tributyl(octanoyloxy)stannane 
• 7319-86-0 lead 2-ethylhexoate 
• 142-82-5 n-heptane 
• 124-07-2 Octanoic acid 

Relevant articles and documents

Structural Studies of Donor-Free and Donor-Solvated Sodium Carboxylates

Focusing mainly on sodium 2-ethylhexanoate, this study reveals that the carboxylate exists as a dimer in MeOD solution as evidenced by Diffusion Ordered NMR SpectroscopY (DOSY). Two crystalline varieties with distinct polymeric structures have been synthesised and crystallographically characterised. A mixed 1,10-phenanthroline–water solvate [{(C5H10)(C2H5)COONa.(H2O)[1,10-phen]}2]∞ contains dimeric [Na(OH2)]2 subunits, which propagate through hydrogen bonds between O atoms of the carboxylate and OH water bonds. Adjacent polymeric chains interdigitate with each other through π?π interactions between 1,10-phen rings. Solvent-free sodium 2-ethylhexanoate has five-coordinate cations comprising one bidentate chelating and three monodentate carboxylate oxygen atoms. Here, the packing arrangement is different with the central hydrophilic (NaO2)∞ core surrounded by a wrapping of disordered alkyl groups. A similar polymeric structure is observed for the crystalline DMSO-solvated sodium valproate [{(C3H7)(C4H8)COONa.(DMSO)}]∞. This adopts a layered arrangement comprising alternating sodium carboxylate hydrophilic layers and hydrophobic organic bilayers.

TARGETED NANOPARTICLES OF WELL-DEFINED AND REPRODUCIBLE SIZES

The invention relates to a nanoparticle preparation comprising nanoparticles of well-defined and reproducible sizes, that are substantially free of aggregate formation.

A green resolution-separation process for aliphatic secondary alcohols

In order to obtain both enantiomers of aliphatic secondary alcohols via a greener method, the four-step resolution-separation process involving lipase-catalyzed enantioselective esterification and hydrolysis as well as two separation procedures both via heterogeneous azeotropic distillation was developed. (S)-2-Pentanol (ee = 98.6%), (R)-2-pentanol (ee >99%), (S)-2-octanol (ee = 98.2%), and (R)-2-octanol (ee = 98.5%) were all produced in high purity (>98%) and high yield (>90%). In addition to the two model substrates, this method could also be applied to the resolution of other aliphatic secondary alcohols.