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(4-Trifluoromethyl-pyridin-3-yl)-methanol, also known as 4-(Trifluoromethyl)-3-pyridinemethanol, is a chemical compound characterized by its molecular formula C7H6F3NO. It is a white crystalline solid that serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. (4-Trifluoromethyl-pyridin-3-yl)-methanol is a derivative of pyridine, featuring a six-membered heterocyclic ring with one nitrogen atom. The distinctive trifluoromethyl group attached to the pyridine ring endows it with unique reactivity and the capacity to significantly influence the physicochemical properties of molecules in which it is incorporated. The chemical structure of (4-Trifluoromethyl-pyridin-3-yl)-methanol positions it as a valuable building block for the preparation of a variety of biologically active compounds.

198401-76-2

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198401-76-2 Usage

Uses

Used in Pharmaceutical Industry:
(4-Trifluoromethyl-pyridin-3-yl)-methanol is utilized as a synthetic intermediate for the development of various pharmaceuticals. Its unique reactivity and the presence of the trifluoromethyl group contribute to the creation of new drugs with improved potency and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, (4-Trifluoromethyl-pyridin-3-yl)-methanol is employed as a building block in the synthesis of novel agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection, potentially leading to increased agricultural yields and reduced chemical usage.
Used in Organic Synthesis:
(4-Trifluoromethyl-pyridin-3-yl)-methanol is used as a reagent in organic synthesis processes. Its distinctive properties allow for the creation of a wide range of chemical entities with diverse applications across various industries, including the development of new materials and the improvement of existing ones.

Check Digit Verification of cas no

The CAS Registry Mumber 198401-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,4,0 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 198401-76:
(8*1)+(7*9)+(6*8)+(5*4)+(4*0)+(3*1)+(2*7)+(1*6)=162
162 % 10 = 2
So 198401-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3NO/c8-7(9,10)6-1-2-11-3-5(6)4-12/h1-3,12H,4H2

198401-76-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(trifluoromethyl)pyridin-3-yl]methanol

1.2 Other means of identification

Product number -
Other names 3-hydroxymethyl-4-trifluoromethylpyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:198401-76-2 SDS

198401-76-2Relevant academic research and scientific papers

COMPOUNDS AND USES THEREOF

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Paragraph 0894; 0965, (2019/11/11)

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

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Page/Page column 197, (2010/12/18)

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.

SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

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Page/Page column 67-68, (2010/11/24)

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

Herbicide compositions

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Page/Page column 35, (2010/02/14)

A herbicidal composition which comprises i) an isoxazoline derivative represented by the following general formula (I) or its salt and ii) at least one compound selected from the Group A: Formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the specification.

ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT

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Page/Page column 200-201, (2010/02/07)

An isoxazoline derivative represented by the following general formula [I]: wherein R1 and R2 may be the same or different and are each an alkyl group; ???R3, R4, R5 and R6 are each a hydrogen atom; ???Y is an optionally substituted 5- to 6-membered aromatic heterocyclic group or fused aromatic heterocyclic group having a hetero atom selected from a nitrogen atom, a oxygen atom and a sulfur atom; and ???n is an integer of 0 to 2. The isoxazoline derivative has an excellent herbicidal effect and an excellent selectivity between crop and weed.

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