19846-20-9 Usage
Description
3-Amino-2,6-dichloro-benzonitrile, a chemical compound with the molecular formula C7H3Cl2N, is a white to off-white solid that is sparingly soluble in water. It serves as a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and dyes, making it a valuable component in medicinal chemistry and agricultural chemistry.
Uses
Used in Pharmaceutical Industry:
3-Amino-2,6-dichloro-benzonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its potential role in the development of antipsychotic and antihypertensive drugs. Its unique chemical structure contributes to the creation of novel therapeutic agents that address unmet medical needs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-2,6-dichloro-benzonitrile is utilized as a precursor in the production of herbicides, insecticides, and fungicides. Its incorporation into these products enhances their effectiveness in controlling pests and diseases, thereby improving crop yields and quality.
Used in Dye Industry:
3-Amino-2,6-dichloro-benzonitrile also finds application in the dye industry, where it serves as a crucial component in the synthesis of various dyes. Its presence in dye formulations contributes to the development of vibrant colors and improved dye performance in different substrates.
Overall, 3-Amino-2,6-dichloro-benzonitrile's diverse applications across industries highlight its significance as a chemical intermediate, driving research and innovation in drug discovery, agriculture, and dye manufacturing.
Check Digit Verification of cas no
The CAS Registry Mumber 19846-20-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,4 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19846-20:
(7*1)+(6*9)+(5*8)+(4*4)+(3*6)+(2*2)+(1*0)=139
139 % 10 = 9
So 19846-20-9 is a valid CAS Registry Number.
19846-20-9Relevant articles and documents
Aromatic C-H amination in hexafluoroisopropanol
D'Amato, Erica M.,B?rgel, Jonas,Ritter, Tobias
, p. 2424 - 2428 (2019/02/28)
We report a direct radical aromatic amination reaction that provides unprotected anilines with an improvement in the substrate scope compared to prior art. Hydrogen bonding by the solvent hexafluoroisopropanol to anions of cationic species is responsible for increased reactivity and can rationalize the enhancement in substrate scope. Our findings may have bearings on radical additions to arenes for direct C-H functionalization in general.
HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS
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Page/Page column 56, (2013/03/26)
The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.
