19846-20-9 Usage
General Description
3-Amino-2,6-dichloro-benzonitrile is a chemical compound with the molecular formula C7H3Cl2N. It is a white to off-white solid that is sparingly soluble in water. 3-Amino-2,6-dichloro-benzonitrile is often used as a building block in the synthesis of pharmaceuticals, agrochemicals, and dyes. It has several applications in the field of medicinal chemistry, particularly in the development of antipsychotic and antihypertensive drugs. Additionally, 3-Amino-2,6-dichloro-benzonitrile is also used in the production of herbicides, insecticides, and fungicides. Due to its potential uses as an intermediate in various chemical processes, this compound is of interest to researchers and industries involved in drug discovery and agricultural chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 19846-20-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,4 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19846-20:
(7*1)+(6*9)+(5*8)+(4*4)+(3*6)+(2*2)+(1*0)=139
139 % 10 = 9
So 19846-20-9 is a valid CAS Registry Number.
19846-20-9Relevant articles and documents
Aromatic C-H amination in hexafluoroisopropanol
D'Amato, Erica M.,B?rgel, Jonas,Ritter, Tobias
, p. 2424 - 2428 (2019/02/28)
We report a direct radical aromatic amination reaction that provides unprotected anilines with an improvement in the substrate scope compared to prior art. Hydrogen bonding by the solvent hexafluoroisopropanol to anions of cationic species is responsible for increased reactivity and can rationalize the enhancement in substrate scope. Our findings may have bearings on radical additions to arenes for direct C-H functionalization in general.
HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS
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Page/Page column 56, (2013/03/26)
The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.
