198471-69-1Relevant academic research and scientific papers
LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER
-
Page/Page column 141, (2010/02/11)
The present invention provides a large conductance calcium-activated K channel opener comprising a compound of the formula (I): wherein R1 and R3 are each sulfonamide, carbamoyl, acyl, amino, and the like, m and n are each 0 to 2, R2 and R4 are each cyano, nitro, hydroxyl, an alkoxy, a halogen, or an alkyl, Ring A is benzene or a heterocyclic ring, Ring B is benzene, a heterocyclic ring, a cycloalkane etc, and Ring Q is pyrazole or isoxazole, or a pharmaceutically acceptable salt thereof as an active ingredient.
Prodrugs of benzenesulfonamide-containing COX-2 inhibitors
-
, (2008/06/13)
Prodrugs of COX-2 inhibitors are described as being useful in treating inflammation and inflammation-related disorders.
