198565-90-1Relevant academic research and scientific papers
A short synthesis of azasugars via aldol reaction of chelated amino acid ester enolates
Grandel, Roland,Kazmaier, Uli
, p. 8009 - 8012 (2007/10/03)
Aldol reactions of chelated amino acid ester enolates with chiral aldehydes gives rise to polyhydroxylated amino acids in a highly stereoselective fashion. These oxygenated amino acids can be converted into polyhydroxylated pipecolinic acids and azasugars by cyclization using the Mitsunobu reaction. A interesting epimerization was observed during the cyclization.
