198631-09-3Relevant articles and documents
Nitrosubstituted hydroxamate ligands in new triphenyltin(IV) complexes as prospective antimicrobial agents
Kumari, Shilpa,Sharma, Neeraj
, p. 584 - 599 (2019)
New triphenyltin(IV) hydroxamate complexes, [Ph3Sn(4-NO2CnH)] and [Ph3Sn(4-NO2BzH)] have been synthesized by the reactions of Ph3SnCl with potassium 4-nitrocinnamo hydroxamate [4-NO2C6H4CHCHCONHOK] (KHL1) and potassium 4-nitro benzohydroxamate [4-NO2C6H4CONHOK] (KHL2). The complexes were synthesized in 1:1 molar ratio in MeOH + C6H6 and characterized by physicochemical and IR, 1H NMR, and mass spectrometry. The bidentate hydroxamate involving bonding through carbonyl and hydroxamic oxygen (O, O coordination) has been inferred from IR spectra. The electrochemical behavior of complexes has been analyzed. Quasi-irreversible two electron metal-centered cathodic process of type SnIV/SnII redox couple was indicated by cyclic voltammetric technique. The thermal behavior of 1 and 2 studied by TGA has shown continuous decomposition to yield Sn + 0.5SnO2 and SnO2 as final residues. The in vitro antimicrobial activity assays of 1 and 2 against pathogenic Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus), Gram-negative bacteria (Salmonella typhi and Pseudomonas aeruginosa), and fungi (Aspergillus fumigatus and Alternaria alternata) were done by MIC method. The complexes have exhibited appreciable antimicrobial activity relative to the respective standard Gentamycin and Nystatin drugs.
Synthesis, characterization and thermal studies of DI- and triphenyltin (IV) complexes of p-chloro- and p-nitrobenzohydroxamic acids
Sharma, Neeraj,Prem, Puneet,Sharma, Vipin,Bhatt,Chaudhry
, p. 1381 - 1397 (2008/10/09)
Di- and triphenyltin(IV) complexes of the compositions Ph2SnCln (XBHA)2-n and Ph3Sn(XBHA) (where n=O or 1, X=p-Cl or p-NO2 and BHA=anion of the hydroxamic acid, BH2A) have been synthesized by the reactions of Ph2SnCl2 or Ph3SnCl with the potassium salts of the respective p-chloro or p-nitrobenzohydroxamic acids in a MeOH/THF mixture. The complexes have been characterized by elemental analyses, molar conductance, molecular weight determinations and IR spectra. The results indicate that the ligand is bidentate, coordinating through the carbonyl and hydroxylamine oxygens. The reactions of Ph2SnCl(XBHA) with sodium derivatives of acetylacetone, dibenzoylmethane and salicylaldehyde (NaL) have led to the formation of mixed ligand complexes of the type Ph2Sn(XBHA). L Thermal decomposition of the complexes in an air stream yielded pure SnO2 at 700-800 °C.
