19865-83-9 Usage
Uses
Used in Pharmaceutical Industry:
(13α,17α)-6α-Acetoxy-21,23-epoxy-7α-hydroxy-4,4,8-trimethyl-24-nor-5α-chola-14,20,22-trien-3-one is used as a pharmaceutical agent for the treatment of hormonal disorders and related conditions. Its unique structural features and biological activity contribute to its potential therapeutic effects in managing such disorders.
Used in Medical Research:
In the field of medical research, (13α,17α)-6α-Acetoxy-21,23-epoxy-7α-hydroxy-4,4,8-trimethyl-24-nor-5α-chola-14,20,22-trien-3-one serves as a valuable compound for studying the effects of complex steroid derivatives on hormonal regulation and related physiological processes. Its specific chemical properties make it a promising candidate for the development of new therapeutic agents and a deeper understanding of hormonal disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 19865-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,6 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19865-83:
(7*1)+(6*9)+(5*8)+(4*6)+(3*5)+(2*8)+(1*3)=159
159 % 10 = 9
So 19865-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C28H38O5/c1-16(29)33-22-23-25(2,3)21(30)10-13-27(23,5)20-9-12-26(4)18(17-11-14-32-15-17)7-8-19(26)28(20,6)24(22)31/h8,11,14-15,18,20,22-24,31H,7,9-10,12-13H2,1-6H3/t18-,20+,22+,23-,24+,26-,27+,28?/m0/s1
19865-83-9Relevant academic research and scientific papers
Chemical Transformations of 6α-Acetoxyazadirone and Two-dimensional NMR Studies on Tetranortriterpenoids
Patra, Amarendra,Mandal, Tarun Kumar,Majumdar, Anadi,Mandal, Kalyan Kumar
, p. 804 - 809 (2007/10/03)
Basic hydrolysis of the tetranortriterpenoid 6α-acetoxyazadirone yielded 6α-hydroxydeacetylazadirone which on preferential acetylation in the cold afforded 6α-acetoxydeacetylazadirone. Treatment of 6α-acetoxyazadirone with hydrogen peroxide-selenium dioxide gave 6- O-acetylisonimocinolide which was a constituent of Chisocheton paniculatus and it underwent acetylation with acetic anhydride-pyridine to 6,21-di-O-acetylisonimocinolide. Careful hydrogenation of 6α-acetoxyazadirone gave 1,2-dihydro as well as 1,2,20,21,22,23- hexahydro derivatives which were hydrolysed under basic conditions to the corresponding 6,7-diol, 6α-Hydroxy-1,2- dihydrodeacetylazadirone so derived furnished meldenin, a minor phytoconstituent of Melia azadirachta, on preferential acetylation in the cold and a triol upon NaBH4 reduction. Acetylation of the latter afforded a triacetate. The structures and nmr assignments of the compounds were settled from two-dimensional homonuclear and heteronuclear correlation (optimized for one-bond and long-range C- H couplings) studies.
