198707-81-2

Basic information

• Product Name: 2-(3-bromophenethyl)benzoic acid
• Synonyms: 2-(3-bromophenethyl)benzoic acid
• CAS NO: 198707-81-2
• Molecular Weight: 305.171
• Mol File: 198707-81-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(3-bromophenethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-bromophenethyl)benzoic acid(198707-81-2)
• EPA Substance Registry System: 2-(3-bromophenethyl)benzoic acid(198707-81-2)

Safety Data

• Hazardous Substances Data: 198707-81-2(Hazardous Substances Data)

Upstream product

• 869070-21-3 2-[2-(3-bromo-phenyl)-vinyl]-benzoic acid 
• 270-75-7 isobenzofuran 
• 128833-03-4 P-[(3-bromophenyl)methyl]phosphonic acid diethyl ester 
• 823-78-9 meta-bromobenzyl bromide 
• 591-17-3 meta-bromotoluene 

Downstream Products

• 198707-82-3 2-bromo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one 
• 869070-31-5 2-phenyl-10,11-dihydro-dibenzo[a,d]cyclohepten-5-one 
• 869070-29-1 {4-[2-(2-bromo-10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-ethylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester 

Relevant articles and documents

MONO HALOGEN OR METHYL-SUBSTITUTED 5-HT2B ANTAGONISTS WITH INCREASED ACTIVITY

Disclose herein are mono halogen or methyl-substituted 5-HT 2B antagonist compounds, which have been found with increased binding activity to 5-HT 2B receptor due to the substitution of halogen or methyl, and the method of using the compounds of treating or preventing a disorder mediated by 5-HT 2B.

NOVEL COMPOUNDS, THEIR PREPARATION AND USE

Novel compounds of the general formula (I), the use of these compounds as phar- maceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPARδ suptype.

Compounds

PCT No. PCT/SE98/00940 Sec. 371 Date Jun. 10, 1998 Sec. 102(e) Date Jun. 10, 1998 PCT Filed May 18, 1998 PCT Pub. No. WO98/54180 PCT Pub. Date Dec. 3, 1998The invention relates to new pharmaceutically active compounds which are P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists, compositions containing them and processes for their preparation.