198760-84-8Relevant articles and documents
Penicillin G acylase mediated synthesis of the enantiopure (S)-3-amino-azetidinl-2-one
Cainelli, Gianfranco,Giacomini, Daria,Galletti, Paola,DaCol, Marco
, p. 3231 - 3235 (1997)
A detailed study of the influence of temperature, pH and enzyme amount on the enantiomeric excess in the enzymatic resolution of N-1 protected 3-amino-azetidin-2-ones with supported PGA is presented. Both enantiomers could be obtained in good enantiomeric
Temperature and solvent effects on enzyme stereoselectivity: Inversion temperature in kinetic resolutions with lipases
Cainelli,De Matteis,Galletti,Giacomini,Orioli
, p. 2351 - 2352 (2007/10/03)
Eyring plots of InE vs. 1/T show inversion temperature in kinetic resolution by lipases, demonstrating that clustering effects in the substrate solvation manage the enzymatic selectivity.