198767-45-2Relevant academic research and scientific papers
Synthesis and action on the central nervous system of 3-substituted 2-phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphorin-4-one 2-oxide and 2-sulfide derivatives
Kostka, Krzysztof,Porada, Marek,Zyner, Elzbieta,Pakulska, Wanda,Szadowska, Anna
, p. 203 - 206 (2007/10/03)
The synthesis of 3-substituted 2-phenyl-2,3-dihydro-4H- 1,3,2-benzoxazaphosphorin-4-one 2-sulfide derivatives is described. The action of a series 2-oxide (1-6) and 2-sulfide (7-12) derivatives on the central nervous system has been evaluated. Compounds 1-4, 6, 7-10 exhibit neuroleptic activity. Derivatives of sulfide series act as antiserotoninergic drugs.
