198823-38-0

Basic information

• Product Name: N-(3-cyanophenyl)-N'-(1-(t-butoxycarbonyl)piperidin-4-yl)urea
• Synonyms: N-(3-cyanophenyl)-N'-(1-(t-butoxycarbonyl)piperidin-4-yl)urea
• CAS NO: 198823-38-0
• Molecular Weight: 344.414
• Mol File: 198823-38-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-cyanophenyl)-N'-(1-(t-butoxycarbonyl)piperidin-4-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-cyanophenyl)-N'-(1-(t-butoxycarbonyl)piperidin-4-yl)urea(198823-38-0)
• EPA Substance Registry System: N-(3-cyanophenyl)-N'-(1-(t-butoxycarbonyl)piperidin-4-yl)urea(198823-38-0)

Safety Data

• Hazardous Substances Data: 198823-38-0(Hazardous Substances Data)

Upstream product

• 16413-26-6 3-cyanophenyl isocyanate 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 

Downstream Products

• 198823-48-2 3-{3-[1-(2-nitro-benzenesulfonyl)-piperidin-4-yl]-2-oxo-[1,3]diazepan-1-yl}-benzonitrile 
• 198823-40-4 3-[2-oxo-3-(1-phenylmethanesulfonyl-piperidin-4-yl)-[1,3]diazepan-1-yl]-benzonitrile 

Relevant articles and documents

The De Novo design and synthesis of cyclic urea inhibitors of Factor Xa: Optimization of the S4 ligand

In this report refinements to the S4 ligand group leads to compound 19, an inhibitor of fXa with good potency in vitro and an improved pharmacokinetic profile in rabbit. The X-ray crystallographic study of a representative analogue confirms our binding model for this series. (C) DuPont Pharmaceuticals Company. Published by Elsevier Science Ltd. All rights reserved.