1989-73-7

Basic information

• Product Name: 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID
• Synonyms: 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID;2-(4-hydroxy-3,5-diMethylphenyl)acetic acid
• CAS NO: 1989-73-7
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• Product Categories: Aromatic Phenylacetic Acids and Derivatives
• Mol File: 1989-73-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID(1989-73-7)
• EPA Substance Registry System: 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID(1989-73-7)

Safety Data

• Hazardous Substances Data: 1989-73-7(Hazardous Substances Data)

Usage

General Description

3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID is a chemical compound with the molecular formula C10H12O3. It is also known as 3,5-dimethyl-4-hydroxyphenylacetic acid. 3,5-DIMETHYL-4-HYDROXYPHENYLACETIC ACID is a derivative of phenylacetic acid and contains a hydroxy and a methyl group attached to the phenyl ring, as well as a carboxylic acid group. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical compounds. It has also been studied for its potential antioxidant and anti-inflammatory properties. This chemical is a white to pale yellow crystalline powder and is soluble in organic solvents such as ethanol and acetone.

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 42900-95-8 4-[(dimethylamino)methyl]-2,6-dimethylphenol 
• 1292298-75-9 4-(2-(4-hydroxy-3,5-dimethylphenyl)-2-oxoethoxy)-4-oxobutan-1-aminium-2,2,2-trifluoroacetate 
• 1610-87-3 (3,5-dimethyl-4-hydroxy-phenyl)-acetonitrile 
• 168106-30-7 3,5-dimethyl-4-benzyloxy-phenyl acetic acid 
• 143-33-9 sodium cyanide 
• 83037-97-2 4-hydroxy-3,5-dimethylbenzyltrimethylammonium iodide 

Downstream Products

• 51511-17-2 (3,5-dimethyl-4-hydroxy-phenyl)-acetic acid methyl ester 

Relevant articles and documents

A simple debenzylation of O-substituted phenol ethers using hydrobromic acid in presence of phase transfer catalyst

A simple methodology for the debenzylation of ortho substituted phenol ethers in two phase system with aqueous hydrobromic acid in the presence of tetrabutylammonium bromide as a phase transfer catalyst is described.

P-Hydroxyphenacyl photoremovable protecting groups Robust photochemistry despite substituent diversity

A broadly based investigation of the effects of a diverse array of substituents on the photochemical rearrangement of p-hydroxyphenacyl esters has demonstrated that common substituents such as F, MeO, CN, CO2R, CONH2, and CH3 have little effect on the rate and quantum efficiencies for the photo-Favorskii rearrangement and the release of the acid leaving group or on the lifetimes of the reactive triplet state. A decrease in the quantum yields across all substituents was observed for the release and rearrangement when the photolyses were carried out in buffered aqueous media at pHs that exceeded the ground-state pKa of the chromophore where the conjugate base is the predominant form. Otherwise, substituents have only a very modest effect on the photoreaction of these robust chromophores.

Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses

This invention relates to poly-substituted derivatives of the N-(benzyl)phenylacetamide type, pharmaceutical compositions comprising same, therapeutic uses thereof, more particularly in the fields of human and animal health. This invention also relates to a process for the preparation of such derivatives.