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19891-85-1

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19891-85-1 Usage

29-Nor-20-oxolupeol

a pentacyclic triterpenoid compound derived from plants

Medicinal properties

anti-inflammatory, anti-tumor, anti-malarial activities
Potential candidate for drug development
Inhibitory effect on the growth of leukemia cells
Potential therapeutic benefits in treatment of neurodegenerative diseases
Antioxidant properties, protecting cells from oxidative damage
Promising in the field of medicine
Potential applications in development of new drugs for various health conditions

Check Digit Verification of cas no

The CAS Registry Mumber 19891-85-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,9 and 1 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 19891-85:
(7*1)+(6*9)+(5*8)+(4*9)+(3*1)+(2*8)+(1*5)=161
161 % 10 = 1
So 19891-85-1 is a valid CAS Registry Number.

19891-85-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-9-hydroxy-3a,5a,5b,8,8,11a-hexamethylicosahydro-1H-cyclopenta[a]chrysen-1-yl)ethan-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19891-85-1 SDS

19891-85-1Downstream Products

19891-85-1Relevant articles and documents

Thompson,Bowers

, p. 845,847 (1968)

-

Jones,Meakins

, (1941)

-

Design and synthesis of new lupeol derivatives and their α-glucosidase inhibitory and cytotoxic activities

Phan, Hoang-Vinh-Truong,Duong, Thuc-Huy,Pham, Duc-Dung,Pham, Hoang-Anh,Nguyen, Van-Kieu,Nguyen, Thi-Phuong,Nguyen, Huu-Hung,Nguyen, Ngoc-Hong,Sam-ang, Pornpat,Phontree, Kiettipum,Sichaem, Jirapast

, p. 1 - 7 (2020/05/13)

A series of lupeol derivatives 2, 2a-2f, 2a-2h, 3a-3e, and 4a-4b were designed, synthesised and evaluated for their α-glucosidase inhibitory and cytotoxic activities. Among synthetic derivatives, lupeol analogues 2b and 2e containing a benzylidene chain exhibited the best activity against α-glucosidase and superior to the positive agent with the IC50 values of 29.4 ± 1.33 and 20.1 ± 0.91 μM, respectively. Lupeol analogues 2d and 3a showed weak cytotoxicity against K562 cell line with the IC50 values of 76.6 ± 2.40 and 94.4 ± 1.51 μM, respectively.

Side chain oxidation of lupeol: A reinvestigation

Roy, Kamal,Bhaduri, A. P.

, p. 823 - 824 (2007/10/03)

Oxidation of lupeol with m-chloroperbenzoic acid yields lup-20-norketone-3β-ol (6), lup-20(29)-ene-3β,30-diol (7) and lup-20-al-3β-ol (8).Formation of the compounds 7 and 8 from lupeol is being reported for the first time.

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