19897-30-4

Upstream product

• 561323-19-1 5-hydroxy-5-(3-methoxy-phenethyl)-octahydro-naphthalen-1-one 
• 872824-23-2 5-hydroxy-5-(3-methoxy-phenylethynyl)-octahydro-naphthalen-1-one 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 174708-17-9 (E)-8-(6-Methoxy-3,4-dihydro-1-naphthyl)oct-5-enoic acid 
• 1027518-51-9 Methanesulfonic acid (E)-7-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-hept-4-enyl ester 
• 174708-21-5 (E)-Ethyl 7-(6-methoxy-3,4-dihydro-1-naphthyl)hept-5-enoate 
• 174708-13-5 1-(2-[1,3]Dioxolan-2-yl-ethyl)-6-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ol 
• 174708-23-7 (E)-8-(6-Methoxy-3,4-dihydro-1-naphthyl)oct-5-enenitrile 
• 174708-22-6 (E)-7-(6-Methoxy-3,4-dihydro-1-naphthyl)hept-4-en-1-ol 
• 174708-14-6 2-(2’-(6’’-methoxy-3’’,4’’-dihydronaphthalen-1’’-yl)ethyl)-1,3-dioxolane 
• 174708-20-4 5-(6-Methoxy-3,4-dihydro-1-naphthyl)pent-1-en-3-ol 
• 174708-15-7 3-(6-Methoxy-3,4-dihydro-1-naphthyl)propanal 
• 174708-19-1 (E)-8-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-oct-5-eneselenoic acid Se-phenyl ester 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 

Downstream Products

• 1091-94-7 (+/-)-estrone methyl ether, C⁽⁹⁾-epimer 
• 10003-13-1 rac-17-((E)-benzylidene)-3-methoxy-D-homo-8α,14β-estra-1,3,5(10)-trien-17a-one 
• 10003-13-1 rac-17-((E)-benzylidene)-3-methoxy-D-homo-9β-estra-1,3,5(10)-trien-17a-one 
• 1091-94-7 (+/-)-3-methoxy-8α-estra-1,3,5(10)-trien-17-one 

Relevant academic research and scientific papers

Consecutive 6-endo trigonal cyclisations from polyene acyl radical intermediates leading to decalone and perhydrophenanthrone ring constructions

A range of substituted Se-phenyl 5,9-dieneselenoates, viz. 15a, 25, 26, 27, 42 and 52, have been synthesised and their reactions with Bu3SnH-AIBN investigated.The diene esters 15a, 42 and 52 are shown to lead to decalone and to perhydrophenanthrone derivatives, viz. 19, 43 and 53, respectively, via consecutive 6-endo trig modes of cyclisations starting from the corresponding 5,9-diene acyl radical intermediates.By contrast, the 5,9-dienoates 25 and 27 lacking alkyl substitution at C-9 instead underwent cyclisation to the indanones 36 and 37, respectively, and the 6-methyl substituted analogue 26 produced only the cyclopentanone 38 on treatment with Bu3SnH-AIBN.