198994-00-2Relevant academic research and scientific papers
Recent progress on the iterative construction of 4-substituted-3-hydroxy benzoic acids from unsaturated aldehydes and dimethyl succinate
Brenna, Elisabetta,Fuganti, Claudio,Perozzo, Valentina,Serra, Stefano
, p. 15029 - 15040 (1997)
An improvement of a known two step cyclization procedure, affording 4-aryl-3-hydroxy benzoic acid derivatives from 3-aryl-2,3-unsaturated aldehydes and dimethyl succinate, is described. The high versatility of the synthetic procedure is shown, as the aryl substituent can be a benzene or naphthalene moiety, or an heteroaromatic ring. It can be applied iteratively to prepare p,p'-oligophenyl derivatives.
