199006-54-7 Usage
Chemical Properties
White powder
Uses
N-Fmoc-4-methyl-L-phenylalanine is used as pharmaceutical intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 199006-54-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,0,0 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 199006-54:
(8*1)+(7*9)+(6*9)+(5*0)+(4*0)+(3*6)+(2*5)+(1*4)=157
157 % 10 = 7
So 199006-54-7 is a valid CAS Registry Number.
InChI:InChI=1/C25H23NO4/c1-16-10-12-17(13-11-16)14-23(24(27)28)26-25(29)30-15-22-20-8-4-2-6-18(20)19-7-3-5-9-21(19)22/h2-13,22-23H,14-15H2,1H3,(H,26,29)(H,27,28)/t23-/m0/s1
199006-54-7Relevant articles and documents
Ligand-Enabled β-C–H Arylation of α-Amino Acids Without Installing Exogenous Directing Groups
Chen, Gang,Zhuang, Zhe,Li, Gen-Cheng,Saint-Denis, Tyler G.,Hsiao, Yi,Joe, Candice L.,Yu, Jin-Quan
, p. 1506 - 1509 (2017)
Herein we report acid-directed β-C(sp3)-H arylation of α-amino acids enabled by pyridine-type ligands. This reaction does not require the installation of an exogenous directing group, is scalable, and enables the preparation of Fmoc-protected unnatural amino acids in three steps. The pyridine-type ligands are crucial for the development of this new C(sp3)-H arylation.