19910-29-3

Basic information

• Product Name: 2,3,3-TRIMETHYLBUTANOIC ACID
• Synonyms: 2,3,3-TRIMETHYLBUTANOIC ACID;RARECHEM AQ A3 0005;Butanoic acid,2,3,3-triMethyl-
• CAS NO: 19910-29-3
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.18
• Mol File: 19910-29-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 24.5 °C
• Boiling Point: 203.6 °C at 760 mmHg
• Flash Point: 88.5 °C
• Appearance: /
• Density: 0.935 g/cm³
• PKA: 4.83±0.16(Predicted)
• CAS DataBase Reference: 2,3,3-TRIMETHYLBUTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,3-TRIMETHYLBUTANOIC ACID(19910-29-3)
• EPA Substance Registry System: 2,3,3-TRIMETHYLBUTANOIC ACID(19910-29-3)

Safety Data

• Hazardous Substances Data: 19910-29-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 6173, 1992 DOI: 10.1021/jo00049a024

Upstream product

• 5340-45-4 3,4,4-trimethyl-2-pentanone 

Downstream Products

• 1427179-51-8 2,6-dimethylphenyl 2,3,3-trimethylbutanoate 
• 1427179-81-4 (Z)-(2,2,3-trimethyloct-3-en-4-yl)benzene 
• 76698-21-0 N-(2,6-Dimethylphenyl)-2,3,3-trimethylbutanamid 
• 616-51-3 1,2,2-trimethyl propyl acetate 
• 105627-23-4 N-(2-Amino-phenyl)-2,3,3-trimethyl-butyramide 
• 76698-22-1 2,3,3-Trimethyl-N-(2,4,6-trimethylphenyl)butanamid 

Relevant articles and documents

CATALYTIC CARBOXYLATION OF ACTIVATED ALKANES AND/OR OLEFINS

The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-containing products. It is a special feature of the method of the present invention that the carboxylation predominantly takes place at a preferred position of the molecule irrespective of the position of the activating group. The carboxylation position is either an aliphatic terminus of the molecule or it is a carbon atom adjacent to a carbon carrying an electron withdrawing group. The course of the reaction can be controlled by appropriately choosing the reaction conditions to yield the desired regioisomer.