19916-74-6Relevant academic research and scientific papers
Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids
Kamble, Nilesh R.,Sigurdsson, Snorri Th.
, p. 4157 - 4164 (2018)
A series of purine-based spin labels was prepared for noncovalent spin-labeling of abasic sites of duplex nucleic acids through hydrogen bonding to an orphan base on the opposing strand and π-stacking interactions with the flanking bases. Both 1,1,3,3-tet
8-substituted O6-benzylguanine, substituted 6(4)-(benzyloxy)pyrimidine, and related derivatives as inactivators of human O6-alkylguanine-DNA alkyltransferase
Chae,Swenn,Kanugula,Dolan,Pegg,Moschel
, p. 359 - 365 (2007/10/02)
Several 8-substituted O6-benzylguanines, 2- and/or 8-substituted 6- (benzyloxy)purines, substituted 6(4)-(benzyloxy)pyrimidines, and a 6- (benzyloxy)-s-triazine were tested for their ability to inactivate the human DNA repair protein, O6/
