199169-85-2Relevant academic research and scientific papers
NOVEL FXR (NR1H4) MODULATING COMPOUNDS
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Page/Page column 62, (2016/07/05)
The present invention relates to compounds which bind to the NR1 H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
CASPASE INHIBITORS CONTAINING DICARBONYLAMINO-ISOXAZOLINE
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Page/Page column 27, (2010/10/20)
The present invention relates to a dicarbonylamino-isoxazoline derivative as an inhibitor against various caspases and a therapeutic composition for preventing inflammation and apoptosis comprising the same.
Cycloaddition of functionalized nitrile oxides and fulminic acid to [60]fullerene
Irngartinger, Hermann,Weber, Anton,Escher, Thomas
, p. 1845 - 1850 (2007/10/03)
Cycloaddition of nitrile oxides to [60]fullerene led to [60]fullereno[1,2-d]isoxazole derivatives 1b-d. [60]Fullereno[1,2-d]isoxazole (1a) is the corresponding cycloadduct with fulminic acid. X-ray structure analyses of compound 1b and 1e were determined. VCH Verlagsgesellschaft mbH, 1996.
