199184-05-9

Upstream product

• 76-83-5 trityl chloride 
• 225091-50-9 5-[(1S,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentyl]-1H-tetrazole 
• 225091-45-2 [(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentyl]methanol 
• 201208-25-5 (1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentanecarboxamide 
• 199184-03-7 (Z)-3-[5-((3aS,4S,6R,6aR)-6-Benzoyloxymethyl-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl)-tetrazol-2-yl]-pent-2-enedioic acid dimethyl ester 
• 199184-04-8 3-((3aS,4S,6R,6aR)-6-Benzoyloxymethyl-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl)-5-methoxycarbonylmethyl-1H-pyrazole-4-carboxylic acid methyl ester 
• 153439-68-0 Benzoic acid (3aR,4R,6S,6aS)-2,2-dimethyl-6-(2H-tetrazol-5-yl)-tetrahydro-cyclopenta[1,3]dioxol-4-ylmethyl ester 
• 120461-65-6 dimethyl 3-chloro-2-pentenedioate 
• 50345-02-3 (1S,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentanecarbonitrile 
• 85026-58-0 (1R,5R,6R,7S)-6,7-(isopropylidenedioxy)-3-oxabicyclo[3.2.1]octane-2-one 
• 225091-51-0 (E)-3-[5-((3aS,4S,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl)-tetrazol-2-yl]-pent-2-enedioic acid dimethyl ester 

Downstream Products

• 199184-07-1 3-[(1S,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentyl]-1H-pyrazolo[4,3-c]pyridine-4,6(5H,7H)-dione 
• 225091-53-2 2-{5-[(1S,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(trityloxymethyl)cyclopentyl]-4-methoxycarbonyl-1H-pyrazolyl-3}acetamide 

Relevant academic research and scientific papers

Chiral synthons for CARBA-β-D-ribonucleosides. Synthesis of CARBA-4- deoxypyrazofurin and isomeric CARBA-4-deaza-oxoformycin analogues

Multi-step transformation of enantiomerically pure synthons, (1S,2S,3R,4R)-(4-hydroxymethyl-2,3-isopropylidenedioxy-1-cyclopentyl) methyl butyrate {(-)-5} and (1R,5R,6R,7S)-6,7-(isopropylidenedioxy)-3- oxabicyclo[3.2.1]octane-2-one {(+)-11} into carba-4-deoxypyrazofurin 1 and isomeric carba-4-deaza-oxoformycin 2 analogues is presented.

The synthesis of enantiomerically pure pyrazolo[4,3-C]pyridine carbaribo C-nucleoside

The synthesis of (-)-3-[(1S,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl) cyclopentan-1-yl]-1H-pyrazolo[4,3-c]pyridine-4,6(5H,7H)-dione 3 was accomplished via enantiomerically pure carbocyclic 5-(β-D- ribofuranosyl)tetrazole 4.