199292-96-1

Basic information

• Product Name: 5-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzoxazole
• Synonyms: 5-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzoxazole
• CAS NO: 199292-96-1
• Molecular Weight: 245.324
• Mol File: 199292-96-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzoxazole(199292-96-1)
• EPA Substance Registry System: 5-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzoxazole(199292-96-1)

Safety Data

• Hazardous Substances Data: 199292-96-1(Hazardous Substances Data)

Upstream product

• 4318-37-0 1-Methylhomopiperazine 
• 10531-78-9 5-methyl-1,3-benzoxazole 
• 22876-22-8 5-methylbenzo[d]oxazole-2-thiol 

Relevant articles and documents

Iodine-catalyzed amination of benzoxazoles: A metal-free route to 2-aminobenzoxazoles under mild conditions

A facile metal-free route of oxidative amination of benzoxazole by activation of C-H bonds with secondary or primary amines in the presence of catalytic iodine in aqueous tert-butyl hydroperoxide proceeds smoothly at ambient temperature (Figure presented) under neat reaction condition to furnish the high yield of the aminated product. This user-friendly method to form C-N bonds produces tertiary butanol and water as the byproduct, which are environmentally benign. The application of the methodology is demonsrated by synthesizing therapeutically active benzoxazoles.