1993-10-8Relevant academic research and scientific papers
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
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, (2018/05/24)
The present invention provides compounds, compositions thereof, and methods of using the same.
Bis-(Sulfonylamino) Derivatives in Therapy 205
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Page/Page column 88-89, (2009/07/10)
The invention provides compounds of formula (I) wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmac
3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: Effect of 6,7-disubstitution on potency and tissue selectivity
De Tullio, Pascal,Boverie, Stéphane,Becker, Bénédicte,Antoine, Marie-Hélène,Nguyen, Quynh-Anh,Francotte, Pierre,Counerotte, Stéphane,Sebille, Sophie,Pirotte, Bernard,Lebrun, Philippe
, p. 4990 - 5000 (2007/10/03)
A series of 6,7-disubstituted 4H-1,2,4-benzothiadiazine 1,1-dioxides bearing a short alkylamino side chain in the 3-position were synthesized. These compounds were tested on rat pancreatic islets and on rat aorta rings. In vitro data indicated that in mos
Fluorinated Heterocycles: I. New 1,4-Benzothiazines and 1,2,4-Benzothiadiazines
Vysokov,Charushin,Chupakhin,Pashkevich
, p. 428 - 433 (2007/10/03)
Chlorosulfonation of 3,4-difluoroaniline gave 2-amino-4,5-difluorobenzenesulfonyl chloride which was converted into the corresponding sulfonamide and sulfinic acid. The latter were used to synthesize various fluorine-containing 1,4-benzothiazine and 1,2,4
