5-Fluor-9,10-dihydro-9-oxo-10-methyl-1,2-benzanthracen, also known as 5-fluorouracil (5-FU), is a synthetic pyrimidine analog that plays a significant role in cancer chemotherapy. This chemical compound is structurally similar to the natural pyrimidine uracil, which allows it to be incorporated into RNA and DNA, ultimately disrupting the synthesis of these nucleic acids and inhibiting the growth of cancer cells. 5-FU is primarily used to treat various types of cancer, including colorectal, breast, stomach, and head and neck cancers. Its mechanism of action involves the inhibition of thymidylate synthase, an enzyme essential for DNA synthesis, leading to the accumulation of abnormal DNA structures and cell death. The effectiveness of 5-FU is often enhanced when used in combination with other chemotherapeutic agents, making it a valuable component in cancer treatment regimens.
The CAS Registry Mumber 1994-60-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,9 and 4 respectively; the second part has 2 digits, 6 and 0 respectively. Calculate Digit Verification of CAS Registry Number 1994-60: (6*1)+(5*9)+(4*9)+(3*4)+(2*6)+(1*0)=111 111 % 10 = 1 So 1994-60-1 is a valid CAS Registry Number.