199436-88-9

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 5445-25-0 ethyl 2-bromo-2-(4-chlorophenyl)acetate 
• 122-52-1 triethyl phosphite 

Downstream Products

• 199437-04-2 2-(4-Chloro-phenyl)-3-cyano-2-(diethoxy-phosphoryl)-propionic acid ethyl ester 
• 199436-91-4 N-[2-(4-Chloro-phenyl)-2-(diethoxy-phosphoryl)-ethyl]-phthalamic acid 
• 199436-89-0 2-(4-Chloro-phenyl)-2-(diethoxy-phosphoryl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid ethyl ester 

Relevant academic research and scientific papers

Arylation of phosphoryl-stabilized carbanions with metal π-complexes of aryl chlorides and fluorides

The nucleophilic aromatic substitution of halogen in metal arene π-complexes η6-(ArF)Cr(CO)3 and [η6-(ArHal)FeCp]+[PF6]- (Hal = F,Cl) with phosphoryl-stabilized carbanions ZCH2P(

Arylation of α-substituted diethyl methylphosphonates with π-complexes of haloarenes

Nucleophilic aromatic substitution of halogen in neutral and cationic π-complexes of haloarenes η6-(ArF)Cr(CO)3 and [η6-(ArHlg)FeCp]+[PF6]- (Hlg = F, Cl) by carbanions derived from α-substi

Potential GABAB Receptor Antagonists. X* the Synthesis of Further Analogues of Baclofen, Phaclbfen and Saclofen

In an attempt to obtain new compounds with binding activity at the GABAB receptor site, we report the synthesis of 3-amino-2-arylpropanoic acids, and the sulfonic, phosphonic and hydroxamic acid analogues. In addition, we report the synthesis of the isomer of phaclofen, 3-amino-1-(4-chlorophenyl)-propylphosphonic acid, and the higher homologue of baclofen, 5-amino-2-(4-chlorophenyl)pentanoic acid.