19947-34-3Relevant academic research and scientific papers
Comparative study of microwave assisted and conventional synthesis of furfuraldehyde based hydrazone derivatives and their metal complexes with biological evaluation
Jabeen, Mussarat,Mehmood, Karamat,Khan, Misbahul Ain,Nasrullah, Muhammad,Maqbool, Tahir,Jabeen, Farhat,Afzal, Misbah
, p. 431 - 436 (2017)
A series of acyl hydrazone derivatives were synthesized by the condensation of different hydrazides (benzohydrazide, isoniazid, nicotinic acid hydrazide and salicylhydrazide) and 5-(4′-nitrophenyl) furan-2-carbaldehyde. These hydrazones were subjected for metal complexation to yield copper(II) and nickel(II) complexes using conventional and microwave irradiation method. The microwave method was found to be successful with nearly the same or higher yields and shorter reaction time. The synthesized compounds were characterized by EIMS, CHN analysis, FTIR and NMR spectroscopy. All the synthesized compounds were screened for their antibacterial and antioxidant activities.
