199526-93-7Relevant academic research and scientific papers
Synthesis of highly substituted N-hydroxyindoles through 1,5-Addition of carbon nucleophiles to in situ generated unsaturated nitrones
Nicolaou,Estrada, Anthony A.,Sang, Hyup Lee,Freestone, Graeme C.
, p. 5364 - 5368 (2006)
(Chemical Equation Presented) As easy as 1→2→3: Generation (1→2) and subsequent capture (2→3) of the reactive α,β-unsaturated nitrone species 2 with silyl enol ethers, silanes, and stannanes leads to a facile and direct entry to a variety of highly substi
New synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin I model systems
Nicolaou,Estrada, Anthony A.,Freestone, Graeme C.,Lee, Sang Hyup,Alvarez-Mico, Xavier
, p. 6088 - 6114 (2008/02/04)
A new synthetic method providing expedient access to a wide range of polyfunctionalized N-hydroxyindoles (IV) is reported. These unique constructs are assembled by nucleophilic additions to in situ generated α,β-unsaturated nitrones (III) through carbon-carbon and carbon-heteroatom bond formation. The new synthetic technology was applied to the synthesis of nocathiacin I (1) model systems (2 and 3a-c) containing the N-hydroxyindole structural motif.
Tricyclic compounds having fungicidal activity, their preparation and their use
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, (2008/06/13)
Compounds of formula (I): STR1 ?wherein: R1 represents halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, cycloalkyl, or cycloalkyloxy; R2 represents hydrogen or halogen; R3 represents hydrogen, alkyl, or cycloalkyl; and the dotted line represents a single or double carbon--carbon bond!; and salts thereof have valuable fungicidal activities which make them of considerable value in agriculture and horticulture.
