199541-42-9Relevant academic research and scientific papers
Synthesis and biological evaluation of potent, selective, hexapeptide CCK-A agonist anorectic agents
Pierson,Comstock,Simmons,Kaiser,Julien,Zongrone,Rosamond
, p. 4302 - 4307 (2007/10/03)
Cholecystokinin (CCK) is a 33-amino acid peptide with multiple functions in both the central nervous system (via CCK-B receptors) and the periphery (via CCK-A receptors). CCK mediation of satiety via the A-receptor subtype suggest a role for CCK in the ma
Synthesis and Biological Activity of CCK Heptapeptide Analogues. Effects of Conformational Constraints and Standard Modifications on Receptor Subtype Selectivity, Functional Activity in Vitro, and Appetite Suppression in Vivo
Holladay, Mark W.,Bennett, Michael J.,Tufano, Michael D.,Lin, C. W.,Asin, Karen E.,et al.
, p. 2919 - 2928 (2007/10/02)
A series of modifications of the CCK7 analogue (des-NH2)Tyr(SO3-)-Nle-Gly-Trp-Nle-Asp-Phe-NH2 was prepared and tested for binding to guinea pig CCK-A and CCK-B receptors and in CCK-A-mediated functional assays.Selected analogues also were teste
