199589-13-4Relevant academic research and scientific papers
Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: Synthesis and biological effects
Kim,Sack,Tokarski,Qian,Chao,Leith,Kelly,Misra,Hunt,Kimball,Humphreys,Wautlet,Mulheron,Webster
, p. 4126 - 4134 (2000)
Flavopiridol analogues, thio- and oxoflavopiridols which contain a sulfur (16) or oxygen (18) atom tinker between a chromone ring and the hydrophobic side chain, are selective cyclin-dependent kinase 1 (CDK1) inhibitors with an IC50 of 110 and
