19959-71-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(1H-PYRAZOL-4-YL)PYRIDINE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 4-(1H-PYRAZOL-4-YL)PYRIDINE serves as a key building block for the creation of complex molecules. Its pyrazole and pyridine rings facilitate diverse chemical reactions, contributing to the advancement of chemical knowledge and the discovery of new compounds with potential applications in various industries.

InChI:InChI=1/C8H7N3/c1-3-9-4-2-7(1)8-5-10-11-6-8/h1-6H,(H,10,11)

Upstream product

• 28356-58-3 pyridine-4-acetic acid 
• 734533-08-5 3,5-dimethyl-4-(4′-pyridyl)pyrazole 
• 51076-46-1 2-(4-pyridyl)-propan-1,3-dione 

Downstream Products

• 690261-95-1 1-benzyl-4-(1H-pyrazol-4-yl)-1,2,3,6-tetrahydropyridine 
• 1220129-55-4 ethyl 5-{2-[(3-chloro-4-fluorophenyl)amino]-4-[4-(pyridin-4-yl)-1H-pyrazol-1-yl]pyrimidin-5-yl}pyridine-3-carboxylate 

Relevant academic research and scientific papers

Design, synthesis, and biologic evaluation of some novel N-arylpyrazole derivatives as cytotoxic agents

A novel series of N-arylpyrazole derivatives (5a-5d, 7a-7c) has been designed and synthesized via aromatic substitution reaction of N-nonsubstituted pyrazoles with 4-fluoronitrobenzene in the presence of base. The structures of these compounds were establ

A simple and environmentally benign synthesis of polypyridine- polycarboxylic acids

An oxidation method using dilute nitric acid solutions under solvothermal conditions has been developed to synthesise a series of polypyridine- polycarboxylic acids. It has been successfully applied to a range of methyl substituted polypyridines including symmetrical and asymmetrical 2,2′-bipyridines; 2,2′:6′,2″-terpyridines and; 2,2′:6′,2″:6″,2?-tetra-pyridines and yields crystalline polypyridine-polycarboxylic acids in a single step. Simple product recovery through filtration yields a recyclable filtrate. More forcing conditions led to demethylation of the polypyridine ligand most probably via decarboxylation. This simple approach avoids potentially harmful metal-based oxidants and negates any issues associated with the disposal of their resultant (hazardous) waste.

HETEROARYLPIPERIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula (I): (wherein R>12345610 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.