199593-08-3 Usage
General Description
N4-acetyl-5'-(dimethoxytrityl)-2'-O-methylcytidine is a chemical compound that belongs to the category of nucleosides. It is a modified form of cytidine with an acetyl group attached to the N4 position and a dimethoxytrityl group attached to the 5' position. Additionally, a methyl group is attached to the 2'-O position of the ribose sugar. This chemical modification makes it suitable for use in the synthesis of nucleic acids and as a building block for various nucleotide analogs. Its unique structure and properties make it valuable in the field of molecular biology and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 199593-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,5,9 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 199593-08:
(8*1)+(7*9)+(6*9)+(5*5)+(4*9)+(3*3)+(2*0)+(1*8)=203
203 % 10 = 3
So 199593-08-3 is a valid CAS Registry Number.
199593-08-3Relevant articles and documents
Ultrafast cleavage and deprotection of oligonucleotides synthesis and use of C(Ac) derivatives
Reddy,Hanna, Naeem B.,Farooqui, Firdous
, p. 1589 - 1598 (2007/10/03)
We have investigated the use of alkylamines as fast cleavage and deprotection reagents for the solid phase synthesis of oligonucleotides and found methylamine/ammonium hydroxide (or methylamine) as an efficient reagent. The transamination side product formed with the commonly used dC(b2) has been eliminated by the use of dC(Ac) phosphoramidite. This system has successfully been used in the synthesis of oligonucleotides and oligonucleoside phosphorothioates. DMT dC(Ac) hydrogen phosphonate and DMT ribo C(Ac)-2'-OMe phosphoramidite also have been prepared and used in the synthesis of oligonucleotides.