199602-13-6Relevant academic research and scientific papers
Use of N-(4-aryl-thiazol-2-yl)-sulfonamides
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, (2008/06/13)
The invention is concerned with the use of sulfonamide derivatives of the general formula STR1 wherein R signifies lower-alkyl, phenyl, benzyl, naphthyl, pyridyl or thienyl, optionally substituted by one or more lower-alkyl, lower-alkoxy, lower-alkyl carb
Synthesis and biochemical evaluation of N-(4-phenylthiazol-2- yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3- hydroxylase
R?ver, Stephan,Cesura, Andrea M.,Huguenin, Philipp,Kettler, Rolf,Szente, Andre
, p. 4378 - 4385 (2007/10/03)
In this paper we describe the synthesis, structure-activity relationship (SAR), and biochemical characterization of N-(4-phenylthiazol-2- yl)benzenesulfonamides as inhibitors of kynurenine 3-hydroxylase. The compounds 3,4-dimethoxy-N-[4-(3-nitrophenyl)thi
